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TGFBR1-IN-2

CAT: 0931-T203174-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203174-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
733806-89-8
Target
Cytochromes P450, Antibacterial, TGF-beta/Smad
Related Pathways
Microbiology/Virology, Stem Cells, Metabolism
Bioactivity
TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor (KD: 0.01 μM) and antimicrobial agent. It serves as a substrate for cytochrome P450. The compound contains a pyridyl-6-methyl group, essential for inhibiting Mycobacterium tuberculosis, and effectively inhibits non-replicating and persistent strains of this bacterium.
Smiles
N=1C=CC(=CC1)NC=2N=C(N=C3C=CC=CC32)C=4N=C(C=CC4)C
Molecular Formula
C19H15N5
Molecular Weight
313.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C