Delphinidin-3-sambubioside (chloride)

Delphinidin-3-sambubioside (chloride)

• CAS Number: 53158-73-9
• UNSPSC Description: Delphinidin-3-sambubioside (Dp3‐Sam) chloride is an anthocyanin that has orally active anti-inflammatory activity. Delphinidin-3-sambubioside chloride inhibits LPS-induced inflammatory factors release. Delphinidin-3-sambubioside chloride also alleviates hepatic lipid accumulation in HFD rats. Delphinidin-3-sambubioside chloride can be isolated from Hibiscus sabdariffa L.[1][3].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/delphinidin-3-sambubioside-chloride.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O)O)[C@H](OC3=C(C4=CC(O)=C(O)C(O)=C4)[O+]=C(C=C(O)C=C5O)C5=C3)O[C@H](CO)[C@H]1O.[Cl-]
• Molecular Weight: 632.95
• References & Citations: [1]Sogo T, et al. Anti-inflammatory activity and molecular mechanism of delphinidin 3-sambubioside, a Hibiscus anthocyanin. Biofactors. 2015 Jan-Feb;41(1):58-65. |[2]Hou DX, et al. Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway. Arch Biochem Biophys. 2005 Aug 1;440(1):101-9. |[3]Long Q, et al. Delphinidin-3-sambubioside from Hibiscus sabdariffa. L attenuates hyperlipidemia in high fat diet-induced obese rats and oleic acid-induced steatosis in HepG2 cells. Bioengineered. 2021 Dec;12(1):3837-3849. https://pubmed.ncbi.nlm.nih.gov/34281481/
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported