Cyanidin 3-sambubioside (chloride)

Cyanidin 3-sambubioside (chloride)

• CAS Number: 33012-73-6
• UNSPSC Description: Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties[1][2][3].
• Target Antigen: Angiotensin-converting Enzyme (ACE); Influenza Virus
• Type: Natural Products
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/cyanidin-3-sambubioside-chloride.html
• Purity: 98.50
• Solubility: 10 mM in DMSO
• Smiles: OC1=CC(O)=CC2=C1C=C(C(C3=CC(O)=C(C=C3)O)=[O+]2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O[C@H]5[C@@H]([C@H]([C@@H](CO5)O)O)O.[Cl-]
• Molecular Weight: 616.95
• References & Citations: [1]Jung-Chu Cheng, et al. Detection of cyanidin in different-colored peanut testae and identification of peanut cyanidin 3-sambubioside. J Agric Food Chem. 2009 Oct 14;57(19):8805-11.|[2]S Kannan, et al. The inhibitory performance of flavonoid cyanidin-3-sambubiocide against H274Y mutation in H1N1 influenza virus. J Biomol Struct Dyn. 2018 Dec;36(16):4255-4269.|[3]Sang-Jin Lee, et al. Cyanidin-3-O-sambubioside from Acanthopanax sessiliflorus fruit inhibits metastasis by downregulating MMP-9 in breast cancer cells MDA-MB-231. Planta Med. 2013 Nov;79(17):1636-40.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported