CWHM-1552

• Description:

  CWHM-1552 is an orally efficacious inhibitor of P. falciparum with IC50s of 51 nM and 53 nM for 3D7 and Dd2 strain, respectively[1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cwhm-1552.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN(C)C1=CC=C(CC(N[C@@H]2CNC[C@H]2C3=CC=C(C(F)(C)F)C=C3)=O)C=C1

• Molecular Formula:

  C22H27F2N3O

• Molecular Weight:

  387.47

• References & Citations:

  [1]Meyers MJ, et al. 4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N- (4-arylpyrrolidin-3-yl) acetamides. ACS Med Chem Lett. 2019 May, 10 (6) :966-971.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Plasmodium

• CAS Number:

  [2368253-58-9]