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Platensimycin

CAT: 0804-HY-127146Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-127146Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 μM) . Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively) . Platensimycin is a promising agent for overcoming antibiotic resistance.
CAS Number
835876-32-9
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/platensimycin.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(O)C(NC(CC[C@]([C@@]2([H])[C@]34C[C@]5([H])[C@@](C4)(C)O[C@@]2([H])C5)(C)C(C=C3)=O)=O)=C1O
Molecular Formula
C24H27NO7
Molecular Weight
441.47
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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