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Pteropterin (monohydrate)

CAT: 0804-HY-127118ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-127118ASize:1 Each
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Description
Pteropterin (Pteroyltriglutamic) monohydrate is an active form of folate. Pteropterin monohydrate shows inhibiting effect on tumor growth and has broad anticancer activity[1][2].
CAS Number
6164-84-7
Product Name Alternative
Pteroyltriglutamic (monohydrate)
UNSPSC
12352005
Target
Drug Metabolite; Folate Receptor (FR)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pteropterin-monohydrate.html
Solubility
10 mM in DMSO
Smiles
O=C(CC[C@H](NC(CC[C@H](NC(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CN=C3NC(N)=NC(C3=N2)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)O.O
Molecular Formula
C29H35N9O13
Molecular Weight
717.64
References & Citations
[1]Stine ZE, et al. Targeting cancer metabolism in the era of precision oncology. Nat Rev Drug Discov. 2022 Feb;21 (2) :141-162. |[2]Muthu M, et al. Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers? Int J Mol Sci. 2019 Mar 19;20 (6) :1385.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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