Pteropterin (monohydrate)

• UNSPSC Description:

  Pteropterin (Pteroyltriglutamic) monohydrate is an active form of folate. Pteropterin monohydrate shows inhibiting effect on tumor growth and has broad anticancer activity[1][2].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pteropterin-monohydrate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CC[C@H](NC(CC[C@H](NC(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CN=C3NC(N)=NC(C3=N2)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)O.O

• Molecular Weight:

  717.64

• References & Citations:

  [1]Stine ZE, et al. Targeting cancer metabolism in the era of precision oncology. Nat Rev Drug Discov. 2022 Feb;21(2):141-162. |[2]Muthu M, et al. Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers? Int J Mol Sci. 2019 Mar 19;20(6):1385.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  6164-84-7