Pteropterin

• Description:

  Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity[1][2].

• Product Name Alternative:

  Pteroyltriglutamic

• UNSPSC:

  12352005

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pteropterin.html

• Purity:

  99.31

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(CC[C@H](NC(CC[C@H](NC(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CN=C3NC(N)=NC(C3=N2)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)O

• Molecular Formula:

  C29H33N9O12

• Molecular Weight:

  699.63

• References & Citations:

  [1]Stine ZE, et al. Targeting cancer metabolism in the era of precision oncology. Nat Rev Drug Discov. 2022 Feb;21 (2) :141-162. |[2]Muthu M, et al. Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers? Int J Mol Sci. 2019 Mar 19;20 (6) :1385.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [89-38-3]