Eprinomectin-d3

• Description :

  Eprinomectin-d3 (MK-397-d3) is the deuterium-labeled Eprinomectin (HY-12643) . Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity[1][2].

• Product Name Alternative :

  MK-397-d3

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@H]1[C@@H](NC(C([2H])([2H])[2H])=O)[C@@H](OC)C[C@H](O[C@@H]2[C@H](C)O[C@@H](O[C@@H](/C(C)=C/C[C@@H](C3)OC4(O[C@@H](C(C)C)[C@H](C)C=C4)C[C@H]3OC5=O)[C@@H](/C=C/C=C6CO[C@@H]7[C@@]\6(O)[C@H]5C=C(C)[C@H]7O)C)C[C@@H]2OC)O1

• Molecular Formula :

  C49H70D3NO14

• Molecular Weight :

  903.12

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Shoop WL, et al. Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. Int J Parasitol.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported