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BI-1950

CAT: 0804-HY-124040Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124040Size:1 Each
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Description
BI-1950, a chemical probe, is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor. LFA-1 is an essential component in normal immune system function and a target for agent discovery[1].
CAS Number
1159724-42-1
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bi-1950.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN=C2N(C3=CC(Cl)=C(F)C(Cl)=C3)C([C@@](C)(CC4=CC=C(C#N)C=C4)N21)=O)N[C@@H](C)C(NC5(C6=NC=CC=C6)CC5)=O
Molecular Formula
C32H26Cl2FN7O3
Molecular Weight
646.50
References & Citations
[1]Latli, B., et al. Synthesis of highly potent Lymphocyte Function-Associated Antigen-1 Antagonists Labeled with Carbon-14 and with Stable Isotopes, Part 3. Journal of Labelled Compounds and Radiopharmaceuticals.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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