BI-1950

• Description:

  BI-1950, a chemical probe, is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor. LFA-1 is an essential component in normal immune system function and a target for agent discovery[1].

• UNSPSC:

  12352005

• Target:

  Integrin

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bi-1950.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN=C2N(C3=CC(Cl)=C(F)C(Cl)=C3)C([C@@](C)(CC4=CC=C(C#N)C=C4)N21)=O)N[C@@H](C)C(NC5(C6=NC=CC=C6)CC5)=O

• Molecular Formula:

  C32H26Cl2FN7O3

• Molecular Weight:

  646.50

• References & Citations:

  [1]Latli, B., et al. Synthesis of highly potent Lymphocyte Function-Associated Antigen-1 Antagonists Labeled with Carbon-14 and with Stable Isotopes, Part 3. Journal of Labelled Compounds and Radiopharmaceuticals.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1159724-42-1]