Products for Research Use Only
RegisterLogin

LAS191859

CAT: 0804-HY-123596Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-123596Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LAS191859 is an orally active, potent and selective CRTh2 antagonist with an IC50 of 9.58 nM against human CRTh2. LAS191859 can be used for the research of chronic asthma[1].
CAS Number
1420071-13-1
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/las191859.html
Solubility
10 mM in DMSO
Smiles
CCN(CC1=CC(C(F)(F)F)=CC=C1N2C=C(C3=C2N=C(C=C3)C)CC(O)=O)C(C4CC4)=O
Molecular Formula
C24H24F3N3O3
Molecular Weight
459.46
References & Citations
[1]Calbet M, et al. Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy. Pharmacol Res. 2016 Sep;111:208-216.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-101114LAS191954

Alternative Products

CatalogName
GTR19197293-01LAS191859

Popular Products