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LAS191859

CAT: 0931-T27799-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T27799-01Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1420071-13-1
Target
Others, Prostaglandin Receptor
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Others
Bioactivity
LAS191859 is a CRTH2/DP2 antagonist with IC50 values of 7.6, 9.58, 14 and 15.5nM for recombinant guinea pig, human, rat and mouse CRTH2/DP2 receptors, respectively. LAS191859 has a residence time half-life of 21h at CRTh2 that translates into a long-lasting in vivo efficacy that is independent of plasma levels
Smiles
C(N(C(=O)C1CC1)CC)C2=C(N3C=4C(C(CC(O)=O)=C3)=CC=C(C)N4)C=CC(C(F)(F)F)=C2
Molecular Formula
C24H24F3N3O3
Molecular Weight
459.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-123596LAS191859

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