Neladenoson dalanate

CAT: 0804-HY-123353Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123353Size:1 Each
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Description
Neladenoson dalanate (Neladenoson bialanate; BAY-1067197) is a orally active agonist precursor of partial Adenosine A1 Receptor. Neladenoson dalanate has a good pharmacokinetic and safety profile, can be used for the chronic heart diseases[1].
CAS Number
[1239309-58-0]
Product Name Alternative
Neladenoson bialanate; BAY-1067197
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/neladenoson-dalanate.html
Solubility
10 mM in DMSO
Smiles
C[C@H](NC([C@@H](N)C)=O)C(OCCOC1=CC=C(C=C1)C2=C(C(SCC3=CSC(C4=CC=C(C=C4)Cl)=N3)=NC(N5CCCC5)=C2C#N)C#N)=O
Molecular Formula
C35H34ClN7O4S2
Molecular Weight
716.27
References & Citations
[1]Meibom D, et al. Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A1 Receptor Agonist for the Chronic Treatment of Heart Diseases. ChemMedChem. 2017 May 22;12 (10) :728-737.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Adenosine A1 receptor (A1R)

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