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Nigranoic acid

CAT: 0804-HY-122935Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122935Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nigranoic acid is a triterpenoid separated from Schisandra chinensis. Nigranoic acid inhibits HIV-1 reverse transcriptase. Nigranoic acid exhibits protective effects on brain through PARP/AIF signaling pathway in cerebral ischemia-reperfusion animal model[1][2].
CAS Number
39111-07-4
UNSPSC
12352211
Target
HIV; Reverse Transcriptase
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nigranoic-acid.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
OC(CC[C@@]12[C@]3([C@](CC[C@H]2C(C)=C)([H])[C@]4([C@@](C)([C@]([C@H](C)CC/C=C(C)\C(O)=O)([H])CC4)CC3)C)C1)=O
Molecular Formula
C30H46O4
Molecular Weight
470.68
References & Citations
[1]Sun HD, et al. Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase. J Nat Prod. 1996 May;59 (5) :525-7.|[2]Feng T, et al. Protective effects of nigranoic acid on cerebral ischemia-reperfusion injury and its mechanism involving apoptotic signaling pathway. Cell Biochem Biophys. 2015 Jan;71 (1) :345-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV-1

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