SaRI 59-801

• Description :

  SaRI 59-801 is an orally effective hypoglycemic compound with stimulation activity of insulin secretion. SaRI 59-801 decreases blood glucose in several species and to elevate plasma insulin in rats and mice[1][2].

• CAS Number :

  [80565-58-8]

• UNSPSC :

  12352005

• Hazard Statement :

  H301-H315-H319-H335

• Target :

  Insulin Receptor

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Endocrinology; Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/sari-59-801.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C1=C(NC2=C1C=CC=C2)C3=C(ON=C3CC)C)CN(C)C

• Molecular Formula :

  C18H23N3O2

• Molecular Weight :

  313.39

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Hanson RL, et al. Stimulation of insulin secretion from isolated rat islets by SaRI 59-801. Diabetes. 1985;34 (6) :548-552.|[2]Hanson RL, et al. Stimulation of insulin secretion from isolated rat islets by SaRI 59-801. Diabetes. 1985 Jun;34 (6) :548-52.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported