IWP-2-V2

• Description :

  IWP-2-V2 is a IWP-2 (HY-13912) analogue that retains activity against the Wnt/β-catenin pathway[1].

• UNSPSC :

  12352005

• Target :

  Wnt

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/iwp-2-v2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1=NC2=C(S1)C=C(C=C2)C)CSC(N3CC4=CC=CC=C4)=NC5=C(C3=O)SCC5

• Molecular Formula :

  C23H20N4O2S3

• Molecular Weight :

  480.63

• References & Citations :

  [1]Chen B, et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol. 2009 Feb;5 (2) :100-7. doi: 10.1038/nchembio.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [877618-79-6]