(Z) -Lafutidine

• Description :

  (Z) -Lafutidine ((Z) -FRG-8813) is a potent histamine H2 receptor antagonist. (Z) -Lafutidine shows anti-secretory and gastroprotective activities[1].

• Product Name Alternative :

  (Z) -FRG-8813

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Histamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/z-lafutidine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O

• Molecular Formula :

  C22H29N3O4S

• Molecular Weight :

  431.55

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Hirakawa N, et al. A novel histamine 2 (H2) receptor antagonist with gastroprotective activity. II. Synthesis and pharmacological evaluation of 2-furfuryl-thio and 2-furfurylsulfinyl acetamide derivatives with heteroaromatic rings. Chem Pharm Bull (Tokyo) . 1998;46 (4) :616-622.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  H2 Receptor

• CAS Number :

  [206449-93-6]