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Lafutidine (Standard)

CAT: 0804-HY-B0160R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0160R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lafutidine (Standard) is the analytical standard of Lafutidine. This product is intended for research and analytical applications. Lafutidine (FRG-8813) is a histamine H2-receptor antagonist (H2RA), with proven gastric mucosal protective effects. Lafutidine can be used for the research of gastroesophageal reflux disease[1].
CAS Number
118288-08-7
Product Name Alternative
FRG-8813 (Standard)
UNSPSC
12352005
Target
Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/lafutidine-standard.html
Smiles
O=C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O
Molecular Formula
C22H29N3O4S
Molecular Weight
431.55
References & Citations
[1]Motoko Nakano, et al. Possible involvement of host defense mechanism in the suppression of rat acute reflux esophagitis by the particular histamine H2 receptor antagonist lafutidine. Pharmacology. 2012;90 (3-4) :205-11.|[2]Tetsuhiro Sugiyama, et al. Lafutidine facilitates calcitonin gene-related peptide (CGRP) nerve-mediated vasodilation via vanilloid-1 receptors in rat mesenteric resistance arteries. J Pharmacol Sci. 2008 Mar;106 (3) :505-11.|[3]Mitsuaki Okayama, et al. Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on dextran sulfate sodium-induced colonic inflammation through capsaicin-sensitive afferent neurons in rats. Dig Dis Sci. 2004 Oct;49 (10) :1696-704.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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