L-659,989

• Description :

  L-659,989 is an orally active, extremely potent, selective and competitive platelet activating factor (PAF) receptor antagonist[1].

• UNSPSC :

  12352005

• Target :

  Platelet-activating Factor Receptor (PAFR)

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/l-659-989.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(C(OC)=CC([C@@H]2CC[C@H](O2)C3=CC(S(=O)(C)=O)=C(C(OC)=C3)OCCC)=C1)OC

• Molecular Formula :

  C24H32O8S

• Molecular Weight :

  480.57

• References & Citations :

  [1]Hwang SB, et al. Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factor. J Pharmacol Exp Ther. 1988 Aug;246 (2) :534-41.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [113787-28-3]