L-659,989

• UNSPSC Description:

  L-659,989 is an orally active, extremely potent, selective and competitive platelet activating factor (PAF) receptor antagonist[1].

• Target Antigen:

  Platelet-activating Factor Receptor (PAFR)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-659-989.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C(C(OC)=CC([C@@H]2CC[C@H](O2)C3=CC(S(=O)(C)=O)=C(C(OC)=C3)OCCC)=C1)OC

• Molecular Weight:

  480.57

• References & Citations:

  [1]Hwang SB, et al. Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factor. J Pharmacol Exp Ther. 1988 Aug;246(2):534-41.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  113787-28-3