TAK-659 25mg

CAT: 0628-A20450-25Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0628-A20450-25Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1312691-33-0

Chemical Information

Mivavotinib

Mivavotinib is an inhibitor of spleen tyrosine kinase (syk), with potential anti-inflammatory, immunomodulating, and antineoplastic activities. Upon administration, mivavotinib may inhibit the activity of syk, which abrogates downstream B-cell receptor (BCR) signaling and leads to an inhibition of B-cell activation, chemotaxis, adhesion and proliferation. Syk, a BCR-associated non-receptor tyrosine kinase that mediates diverse cellular responses, including proliferation, differentiation, and phagocytosis, is expressed in hematopoietic tissues and is often overexpressed in hematopoietic malignancies.

CAS Number	1312691-33-0
PubChem CID	53252276
IUPAC Name	6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-4-(1-methylpyrazol-4-yl)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Molecular Formula	C17H21FN6O
Molecular Weight	344.4
XLogP	0.5
Topological Polar Surface Area	97.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Heavy Atom Count	25
Formal Charge	0
Complexity	508

SMILES

CN1C=C(C=N1)C2=NC(=C(C3=C2C(=O)NC3)F)N[C@@H]4CCCC[C@@H]4N

InChI

InChI=1S/C17H21FN6O/c1-24-8-9(6-21-24)15-13-10(7-20-17(13)25)14(18)16(23-15)22-12-5-3-2-4-11(12)19/h6,8,11-12H,2-5,7,19H2,1H3,(H,20,25)(H,22,23)/t11-,12+/m0/s1

InChIKey

MJHOMTRKVMKCNE-NWDGAFQWSA-N

Chemical Structure

2D Structure

CAS: 1312691-33-0

CID: 53252276

Formula: C17H21FN6O

MW: 344.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	344.4
XLogP3	0.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	344.17608748
Monoisotopic Mass	344.17608748
Topological Polar Surface Area	97.9 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	508
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
A21885-25	TAK-659 hydrochloride 25mg
A20450-5	TAK-659 5mg
A20450-50	TAK-659 50mg
A20450-100	TAK-659 100mg
A20450-10	TAK-659 10mg
A21885-10	TAK-659 hydrochloride 10mg
A21885-50	TAK-659 hydrochloride 50mg
A21885-100	TAK-659 hydrochloride 100mg
A21885-5	TAK-659 hydrochloride 5mg
A21885-2	TAK-659 hydrochloride 2mg

Alternative Products

Catalog	Name
GTR19201920-01	TAK-659
C18182-25mg	TAK-659 Hydrochloride
206169	TAK-659 HCl
MBS5750071	TAK-659 (hydrochloride)

TAK-659 25mg

Chemical Information

Related Products

Alternative Products

Popular Products