BRD0476

CAT: 0804-HY-120711Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120711Size:1 Each
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Description
BRD0476 is an inhibitor of pancreatic β-cell apoptosis with an EC50 value of 0.78 μM and a maximal inhibitory activity of 99%. BRD0476 can be used in diabetes-related research[1].
CAS Number
[1314958-91-2]
Product Name Alternative
ML187
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/brd0476.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C(C2=CC=C1)O[C@H]([C@@H](CN(C2=O)[C@H](CO)C)C)CN(C)S(=O)(C3=CC=C4OCCOC4=C3)=O)NC5=C6C=CC=CC6=CC=C5
Molecular Formula
C35H38N4O8S
Molecular Weight
674.76
References & Citations
[1]Chou DH, et al. Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis. ACS Med Chem Lett. 2011 Sep 8;2 (9) :698-702.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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