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Darglitazone (Sodium)

CAT: 0804-HY-120160ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120160ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Darglitazone Sodium, a thiazolidinedione, is an orally active, potent, and selective PPAR-γ (peroxisome proliferator-activated receptor) agonist. Darglitazone Sodium is effective in controlling blood glucose and lipid metabolism, and can be used for type II diabetes research[1][2].
CAS Number
149904-87-0
Product Name Alternative
CP 86325 (Sodium)
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/darglitazone-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C([N-]1)SC(CC2=CC=C(C(CCC3=C(C)OC(C4=CC=CC=C4)=N3)=O)C=C2)C1=O.[Na+]
Molecular Formula
C23H19N2NaO4S
Molecular Weight
442.46
References & Citations
[1]Rashmi Kumari, et al. The PPAR-gamma agonist, darglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse. J Cereb Blood Flow Metab. 2010 Feb;30 (2) :352-60.|[2]Hoenig M, Ferguson DC. Effect of darglitazone on glucose clearance and lipid metabolism in obese cats. Am J Vet Res. 2003 Nov;64 (11) :1409-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ

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