FR181157

• Description :

  FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties[1].

• CAS Number :

  [171046-15-4]

• UNSPSC :

  12352005

• Target :

  Prostaglandin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/fr181157.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O[Na])COC1=CC=CC(C[C@H]2C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)O3)=CCCC2)=C1

• Molecular Formula :

  C30H26NNaO4

• Molecular Weight :

  487.52

• References & Citations :

  [1]Kouji Hattori , et al. A simple stereoselective synthesis and biological evaluation of FR181157: orally active prostacyclin mimetic. Bioorg Med Chem Lett. 2003 Dec 15;13 (24) :4277-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported