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Terrein

CAT: 0804-HY-119808-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119808-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Terrein is a melanogenesis inhibitor[1]. Terrein induces apoptosis in breast cancer cell lines [2]. Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa[3].
CAS Number
582-46-7
UNSPSC
12352211
Hazard Statement
H315, H319, H320
Target
Antibiotic; Apoptosis; Melanocortin Receptor
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/terrein.html
Purity
99.44
Solubility
10 mM in DMSO
Smiles
O=C1C=C(/C=C/C)[C@H](O)[C@H]1O
Molecular Formula
C8H10O3
Molecular Weight
154.16
Precautions
H315, H319, H320
References & Citations
[1]S-H Park, et al. Terrein: A New Melanogenesis Inhibitor and Its Mechanism. Cell Mol Life Sci. 2004 Nov;61 (22) :2878-85.|[2]Anongnard Kasorn, et al. Terrein Inhibits Migration of Human Breast Cancer Cells via Inhibition of the Rho and Rac Signaling Pathways. Oncol Rep. 2018 Mar;39 (3) :1378-1386.|[3]Bomin Kim, et al. Terrein Is an Inhibitor of Quorum Sensing and c-di-GMP in Pseudomonas Aeruginosa: A Connection Between Quorum Sensing and c-di-GMP. Sci Rep. 2018 Jun 5;8 (1) :8617.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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