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TMPPAA

CAT: 0804-HY-119806Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119806Size:1 Each
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Description
TMPPAA is an allosteric agonist and positive allosteric modulator of the 5-HT3 receptor. TMPPAA enhances 5-HT-mediated 5-HT3AR signaling[1].
CAS Number
844900-50-1
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tmppaa.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=C(C=C1)OC)NC(CC)CC
Molecular Formula
C15H21NO2
Molecular Weight
247.33
References & Citations
[1]Gasiorek A, et al. Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors. Biochem Pharmacol. 2016 Jun 15;110-111:92-108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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