AA-CW236

• Description :

  AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification[1].

• UNSPSC :

  12352005

• Target :

  DNA Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/aa-cw236.html

• Purity :

  99.9

• Solubility :

  DMSO : 25 mg/mL (ultrasonic; warming)

• Smiles :

  FC(F)(F)OC1=CC=C(C2=C(CCl)N(CCC3=C(C)ON=C3C)N=N2)C=C1

• Molecular Formula :

  C17H16ClF3N4O2

• Molecular Weight :

  400.78

• References & Citations :

  MGMT (O6-methylguanine DNA methyltransferase)

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1869921-96-9]