BTI-A-404

• Description :

  BTI-A-404 is a potent, selective and competitive inverse agonist of human GPR43. BTI-A-404 can be used for the research of inflammation, obesity and type 2 diabetes[1].

• UNSPSC :

  12352005

• Target :

  Free Fatty Acid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/bti-a-404.html

• Purity :

  99.30

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1=CC(C)=CC(C)=C1)C2=C(NC(NC2C3=CC=C(C=C3)N(C)C)=O)C

• Molecular Formula :

  C22H26N4O2

• Molecular Weight :

  378.47

• References & Citations :

  [1]Park BO, et, al. Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. Eur J Pharmacol. 2016 Jan 15;771:1-9.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [537679-57-5]