BTI-A-404

• Description:

  BTI-A-404 is a potent, selective and competitive inverse agonist of human GPR43. BTI-A-404 can be used for the research of inflammation, obesity and type 2 diabetes[1].

• UNSPSC:

  12352005

• Target:

  Free Fatty Acid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bti-a-404.html

• Purity:

  99.30

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC(C)=CC(C)=C1)C2=C(NC(NC2C3=CC=C(C=C3)N(C)C)=O)C

• Molecular Formula:

  C22H26N4O2

• Molecular Weight:

  378.47

• References & Citations:

  [1]Park BO, et, al. Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. Eur J Pharmacol. 2016 Jan 15;771:1-9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [537679-57-5]