MRS1186

CAT: 0804-HY-118678Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-118678Size:1 Each
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Description
MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.
CAS Number
[183721-03-1]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/MRS1186.html
Solubility
10 mM in DMSO
Smiles
CCC(NC1=NC2=C(C3=NC(C4=CC=CO4)=NN13)C=C(C=C2)Cl)=O
Molecular Formula
C16H12ClN5O2
Molecular Weight
341.75
References & Citations
[1]Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49 (14) :4085-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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