Products for Research Use Only
RegisterLogin

Celecoxib-d4

CAT: 0804-HY-118139SSize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-118139SSize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Celecoxib-d4 is the deuterium labeled Desmethyl Celecoxib. Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an?analog?of Celecoxib and with the optimal yield of 75%[1].
CAS Number
544686-20-6
UNSPSC
12352005
Hazard Statement
H302, H319, H372, H410
Target
COX; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=NN(C2=C([2H])C([2H])=C(C([2H])=C2[2H])S(N)(=O)=O)C(C3=CC=C(C=C3)C)=C1)F
Molecular Formula
C17H10D4F3N3O2S
Molecular Weight
385.40
Precautions
H302, H319, H372, H410
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Vinay Kumar Sthalam, et al. An Integrated Continuous Flow Micro-Total Ultrafast Process System (μ-TUFPS) for the Synthesis of Celecoxib and Other Cyclooxygenase Inhibitors. RETURN TO ISSUEPREVARTICLENEXT
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-14398-01Celecoxib
HY-14398R-01Celecoxib (Standard)
HY-145526-01Hydroxy celecoxib
HY-14398S1-01Celecoxib-d3
HY-118139-01Desmethyl Celecoxib
HY-14398GCelecoxib (GMP)
HY-14398S-01Celecoxib-d7
HY-134234-01Celecoxib carboxylic acid
HY-14398GLCelecoxib (GMP Like)
HY-134234RCelecoxib carboxylic acid (Standard)

Alternative Products

CatalogName
TRC-C251002-1MGCelecoxib-d4
TRC-H946582-50MGHydroxy Celecoxib-d4
TRC-D289592-25MGDesmethyl Celecoxib-d4
sc-4986042,5-Dimethyl Celecoxib-d4
TRC-D291817-25MG4-Desmethyl-2-methyl Celecoxib-d4
sc-4998554-Desmethyl-3-methyl Celecoxib-d4
T0466-01Celecoxib

Popular Products