L-669,262

• UNSPSC Description:

  L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC50 of 0.10 ng/mL for rat liver HMG-CoA[1].

• Target Antigen:

  HMG-CoA Reductase (HMGCR)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-669-262.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC(C)(C(O[C@H]1CC(C)=CC2=CC([C@@H]([C@@H]([C@@]12[H])CC[C@@H]3C[C@H](CC(O3)=O)O)C)=O)=O)C

• Molecular Weight:

  432.55

• References & Citations:

  [1]Joshua H, et, al. L-669,262, a potent HMG-CoA reductase inhibitor. J Antibiot (Tokyo). 1991 Mar;44(3):366-70.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  130468-11-0