MSX-2

MSX-2

• CAS Number: 261717-18-4
• UNSPSC Description: MSX-2 is A2A adenosine receptor antagonist, with Ki of 5 nM in human that plays an important role in Parkinson's disease[1][2].
• Target Antigen: Adenosine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/msx-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N(C1=C(C2=O)N(C(/C=C/C3=CC=CC(OC)=C3)=N1)C)CCCO)N2CC#C
• Molecular Weight: 394.42
• References & Citations: [1]Manuel de Lera Ruiz, et al. Adenosine A2A Receptor as a Drug Discovery Target. J Med Chem. 2014 May 8;57(9):3623-50.|[2]Tina Becic, et al. Growth factors FGF8 and FGF2 and their receptor FGFR1, transcriptional factors Msx-1 and MSX-2, and apoptotic factors p19 and RIP5 participate in the early human limb development. Acta Histochem. 2018 Apr;120(3):205-214.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported