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TPN729

CAT: 0804-HY-116808Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116808Size:1 Each
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Description
TPN729 is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM. TPN729 affects erectile function and it can be used for the research of erectile dysfunction[1].
CAS Number
936951-20-1
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tpn729.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(OCCC)C(C(NC2=C3N(C)N=C2CCC)=NC3=O)=C1)(N(C)CCN4CCCC4)=O
Molecular Formula
C25H36N6O4S
Molecular Weight
516.66
References & Citations
[1]Wang Z, et al. The selectivity and potency of the new PDE5 inhibitor TPN729MA. J Sex Med. 2013 Nov;10 (11) :2790-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE1; PDE11; PDE4; PDE5; PDE6

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