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TPN729MA

CAT: 0804-HY-116808B-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116808B-01Size:5 mg
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Description
TPN729MA (TPN729 maleate) is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM. TPN729MA affects erectile function and it can be used for the research of erectile dysfunction[1].
CAS Number
1422955-52-9
Product Name Alternative
TPN729 (maleate)
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tpn729ma.html
Concentration
10mM
Purity
99.45
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(/C=C\C(O)=O)=O.CCCOC1=C(C(NC2=C3N(N=C2CCC)C)=NC3=O)C=C(C=C1)S(N(C)CCN4CCCC4)(=O)=O
Molecular Formula
C29H40N6O8S
Molecular Weight
632.73
References & Citations
[1]Wang Z, et al. The selectivity and potency of the new PDE5 inhibitor TPN729MA. J Sex Med. 2013 Nov;10 (11) :2790-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE1; PDE11; PDE4; PDE5; PDE6

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HY-116808TPN729

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BA8229-10TPN729MA

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