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Trans-Cevimeline (hydrochloride)

CAT: 0804-HY-116459-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116459-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease[1].
CAS Number
107220-29-1
Product Name Alternative
AF102A (hydrochloride)
UNSPSC
12352005
Hazard Statement
H301-H332-H351-H361
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trans-cevimeline-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1SC[C@@]2(CN3CCC2CC3)O1.[H]Cl
Molecular Formula
C10H18ClNOS
Molecular Weight
235.77
Precautions
P261-P264-P270-P271-P280-P304+P340-P330-P405-P501
References & Citations
[1]Fisher A, et al. (+-) -cis-2-methyl-spiro (1,3-oxathiolane-5,3') quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease. J Pharmacol Exp Ther. 1991;257 (1) :392-403.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR1

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