NS5A-IN-2

CAT: 0804-HY-115981Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-115981Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

NS5A-IN-2 (Compound 33) is a potent inhibitor of NS5A. NS5A-IN-2 has extremely high potency against HCV genotype 1b, improved activity against genotype 3a (GT 3a) and good metabolic stability[1]. NS5A-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CAS Number

2764786-74-3

UNSPSC

12352005

Target

HCV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ns5a-in-2.html

Solubility

10 mM in DMSO

Smiles

COC(N[C@H](C1=CC=CC=C1)C(N2CCC[C@H]2C3=NC=C(N3)C4=CC=C(C=C4)C#CC5=CC(NC([C@@H]6CCCN6C([C@@H](C7=CC=CC=C7)NC(OC)=O)=O)=O)=CC=C5)=O)=O

Molecular Formula

C46H45N7O7

Molecular Weight

807.89

References & Citations

[1]Abdallah M, et al. Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier. Eur J Med Chem. 2022;229:114034.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-115982	NS5A-IN-3
HY-146126	NS5A-IN-4
HY-145375	NS5A-IN-1
HY-169815	HCV NS5B polymerase-IN-2
HY-P75704-01	NS5, Dengue virus 2 (His)
HY-W011060-01	Cryptand 2.2.2
HY-B1500-01	2,2,2-Trichloroethanol
HY-N2048-01	2,2':5',2''-Terthiophene
HY-W073314	2,2,2-Trifluoroethoxyamine (hydrochloride)
HY-132268-01	Cav 2.2 blocker 2

Alternative Products

Catalog	Name
GTR19221609-01	NS5A-IN-2
301518	HCV NS5a (Hepatitis C NS5a)
T74403-01	NS5A-IN-1
T73223-01	NS5A-IN-3
E61H00805	HCV NS5a
GWB-ED8650	Hepatitis C NS5a (HCV NS5a), Antibody
MBS5816453	NS5A-IN-4
abx457698-01	Classical Swine Fever Virus NS5A (CSFV NS5A) Antibody
abx021853	HCV NS5A Antibody
E55A11126	CSFV NS5A Antibody

NS5A-IN-2

Related Products

Alternative Products

Popular Products