Lenperone (hydrochloride)

• Description :

  Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research[1][2].

• CAS Number :

  [24677-86-9]

• Product Name Alternative :

  AHR 2277

• UNSPSC :

  12352005

• Target :

  Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/lenperone-hydrochloride.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CCCN1CCC(CC1)C(C2=CC=C(C=C2)F)=O)C3=CC=C(C=C3)F.Cl

• Molecular Formula :

  C22H24ClF2NO2

• Molecular Weight :

  407.88

• References & Citations :

  [1]Johnson SE, et al. Effect of lenperone hydrochloride on gastroesophageal sphincter pressure in healthy dogs. Can J Vet Res. 1989 Apr;53 (2) :248-50.|[2]Costall B, Naylor RJ. Mesolimbic involvement with behavioural effects indicating antipsychotic activity. Eur J Pharmacol. 1974 Jun;27 (1) :46-58.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported