11-Beta-hydroxyandrostenedione-d4
CAT:
804-HY-114464S
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

11-Beta-hydroxyandrostenedione-d4
- CAS Number: 2687960-98-9
- UNSPSC Description: 11-Beta-hydroxyandrostenedione-d4 is the deuterium labeled 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor[1][2].
- Target Antigen: 11β-HSD; Endogenous Metabolite; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Metabolic Enzyme/Protease;Others
- Field of Research: Endocrinology
- Solubility: 10 mM in DMSO
- Smiles: O=C(CCC1C2CCC3=C4)[C@]1(C([2H])([C@@]([2H])([C@@]2([C@]3(CCC4=O)C)[2H])O)[2H])C
- Molecular Weight: 306.43
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Rachelle Gent, et al. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17αhydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported