11-Beta-hydroxyandrostenedione-d7
CAT:
804-HY-114464S1-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

11-Beta-hydroxyandrostenedione-d7
- CAS Number: 2331287-27-3
- UNSPSC Description: 11-Beta-hydroxyandrostenedione-d7 is the deuterium labeled 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor[1][2]
- Target Antigen: 11β-HSD; Endogenous Metabolite
- Type: Isotope-Labeled Compounds
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Others
- Purity: 99.0
- Solubility: 10 mM in DMSO
- Smiles: C[C@@]12[C@]3([H])[C@](CC([2H])([2H])C1=C([2H])C(C([2H])([2H])C2)=O)([H])[C@@]4([H])[C@](C[C@@H]3O)(C(C([2H])([2H])C4)=O)C
- Molecular Weight: 309.45
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Rachelle Gent, et al. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17αhydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported