Perillic acid

CAT: 0804-HY-113471Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-113471Size:1 Each
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Description
Perillic acid is the metabolite of Perillyl alcohol (HY-N7000) . Perillic acid induces lung cancer cell cycle arrest and apoptosis. Perillic acid shows anti-HSV-1 and immunomodulatory activities[1][2][3].
CAS Number
[7694-45-3]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Drug Metabolite; HSV
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/perillic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CCC(C(C)=C)CC1)O
Molecular Formula
C10H14O2
Molecular Weight
166.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Yeruva L, et al. Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells. Cancer Lett. 2007 Nov 18;257 (2) :216-26.|[2]Mello CP, et al. Perillyl alcohol and perillic acid exert efficient action upon HSV-1 maturation and release of infective virus. Antivir Ther. 2020;25 (1) :1-11.|[3]Raphael TJ, et al. Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid. Immunopharmacol Immunotoxicol. 2003 May;25 (2) :285-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSV-1

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