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Cholesteryl oleate-d7

CAT: 0804-HY-113217SSize: 1 mg (1.52 mM x 1 mL in Methylene chloride)Dry Ice: NoHazardous: No
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CAT#:0804-HY-113217SSize:1 mg (1.52 mM x 1 mL in Methylene chloride)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing[1][2][3][4].
CAS Number
1416275-35-8
UNSPSC
12352211
Hazard Statement
H315, H319, H336, H351
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Concentration
1.52 mM * 1 mL in Methylene chloride
Purity
99.0
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(CCCCCCC/C=C\CCCCCCCC)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C
Molecular Formula
C45H71D7O2
Molecular Weight
658.14
Precautions
H315, H319, H336, H351
References & Citations
[1]Souza SL, et al. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chem Phys Lipids. 2011 Oct;164 (7) :664-71.|[2]Suñé-Pou M, et, al. Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy. Int J Nanomedicine. 2018 May 30;13:3223-3233.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[4]Li J, et al. Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer. Sci Rep. 2016 Feb 11;6:20984.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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