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Cholesteryl oleate

CAT: 0804-HY-113217-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113217-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cholesteryl oleate is an ester compound formed from Cholesterol and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing[1][2][3][4].
CAS Number
303-43-5
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Liposome
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Cholesteryl_oleate.html
Purity
99.0
Solubility
Acetone : 50 mg/mL (ultrasonic)|DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : 12.5 mg/mL (ultrasonic;warming;heat to 50°C)
Smiles
CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Molecular Formula
C45H78O2
Molecular Weight
651.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Souza SL, et al. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chem Phys Lipids. 2011 Oct;164 (7) :664-71.|[2]Suñé-Pou M, et, al. Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy. Int J Nanomedicine. 2018 May 30;13:3223-3233.|[3]Li J, et al. Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer. Sci Rep. 2016 Feb 11;6:20984.|[4]Rudel LL, et al. Hepatic origin of cholesteryl oleate in coronary artery atherosclerosis in African green monkeys. Enrichment by dietary monounsaturated fat. J Clin Invest. 1997 Jul 1;100 (1) :74-83.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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