5-Methyltetrahydrofolic acid-13C5

5-Methyltetrahydrofolic acid-13C5

• UNSPSC Description: 5-Methyltetrahydrofolic acid-13C5 is the 13C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid[1].
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/5-methyltetrahydrofolic-acid-13c5.html
• Purity: 98.0
• Solubility: 10 mM in DMSO
• Smiles: CN1C2=C(NCC1CNC3=CC=C(C(N[13C@@H]([13CH2][13CH2][13C](O)=O)[13C](O)=O)=O)C=C3)NC(N)=NC2=O
• Molecular Weight: 464.42
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Wright AJ, et al. Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults. Br J Nutr. 2010 Mar;103(5):724-9.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported