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AM9405

CAT: 0804-HY-112707Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112707Size:1 Each
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Description
AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC50s of 45.71 and 0.076 nM, respectively.
CAS Number
3032946-55-4
UNSPSC
12352005
Target
5-HT Receptor; Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/AM9405.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C2=[N+](C)C(C=CC=C3)=C3N2C)C(O)=CC(C(C)(C)CCCCCC)=C1.[Br-]
Molecular Formula
C24H33BrN2O2
Molecular Weight
461.44
References & Citations
[1]Salaga M, et al. The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. Eur J Pharmacol. 2018 Oct 5;836:34-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1; lactoferrin

Alternative Products

CatalogName
GTR19207235-01AM9405

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