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AM9405

CAT: 0931-T10294-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T10294-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
5-HT Receptor, Cannabinoid Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. It inhibits twitch contraction of the ileum and colon with IC50 values of 45.71 nM and 0.076 nM, respectively. AM9405 significantly slowed mouse intestinal motility under physiological conditions and reversed hypermotility, reducing pain in mouse models that mimic symptoms of functional GI disorders, such as stress-induced diarrhea and writhing test.
Smiles
OC1=C(C2=[N+](C)C(C=CC=C3)=C3N2C)C(O)=CC(C(C)(C)CCCCCC)=C1.[Br-]
Molecular Formula
C24H33BrN2O2
Molecular Weight
461.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19207235-01AM9405

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