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BTO-1

CAT: 0804-HY-112395Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112395Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications[1][2].
CAS Number
40647-02-7
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H319-H332-H335
Target
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bto-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=[N+]([O-])C2=CC(C#N)=CC([N+]([O-])=O)=C2S1)N
Molecular Formula
C9H4N4O4S
Molecular Weight
264.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Peters, U., et al. Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nat Chem Biol 2, 618–626 (2006) .|[2]Brennan IM, et al. Polo-like kinase controls vertebrate spindle elongation and cytokinesis. PLoS One. 2007;2 (5) :e409. Published 2007 May 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLK1

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