(R) -MIK665

CAT: 0804-HY-112218ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-112218ASize:1 Each
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Description
(R) -MIK665 is the less active enantiomer of MIK665. MIK665 is a special Mcl-1 inhibitor with an IC50 of 1.81 nM.
CAS Number
[1799831-02-9]
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-mik665.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](CC(C=CC=C1)=C1OCC2=CC=NC(C3=CC=CC=C3OC)=N2)OC4=C5[C@@]([C@@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)=C(C8=CC=C(F)C=C8)SC5=NC=N4)=O.[R].[R]
Molecular Formula
C47H44ClFN6O6S
Molecular Weight
875.41
References & Citations
[1]Andras Kotschy, et al. New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them. EP2886545A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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