Phaseic acid-d4

• Description :

  Phaseic acid-d4 is the deuterium labeled Phaseic acid. Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission. Phaseic acid is the antagonist for NMDA-type glutamate receptor (NMDAR) that inhibits NMDAR currents with an IC50 of 34.37 μM. Phaseic acid reduces intracellular calcium influx, and exhibits neuroprotective effect[1][2].

• CAS Number :

  [721948-57-8]

• UNSPSC :

  12352005

• Target :

  IGluR; Isotope-Labeled Compounds; Phytohormone

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research :

  Others

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)/C=C(C)\C=C\[C@]1(O)[C@]2(C)C([2H])([2H])C(C([2H])([2H])[C@@]1(C)OC2)=O

• Molecular Formula :

  C15H16D4O5

• Molecular Weight :

  284.34

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported