Phaseic acid-d4

• Description:

  Phaseic acid-d4 is the deuterium labeled Phaseic acid. Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission. Phaseic acid is the antagonist for NMDA-type glutamate receptor (NMDAR) that inhibits NMDAR currents with an IC50 of 34.37 μM. Phaseic acid reduces intracellular calcium influx, and exhibits neuroprotective effect[1][2].

• UNSPSC:

  12352005

• Target:

  IGluR; Isotope-Labeled Compounds; Phytohormone

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research:

  Others

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)/C=C(C)\C=C\[C@]1(O)[C@]2(C)C([2H])([2H])C(C([2H])([2H])[C@@]1(C)OC2)=O

• Molecular Formula:

  C15H16D4O5

• Molecular Weight:

  284.34

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [721948-57-8]