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Imatinib carbaldehyde

CAT: 0804-HY-111849-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111849-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER[1].
CAS Number
1436868-85-7
Product Name Alternative
CGP-57148B carbaldehyde; STI571 carbaldehyde; PROTAC ABL binding moiety 1
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-abl-binding-moiety-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(NC(C2=CC=C(CN3CCN(C=O)CC3)C=C2)=O)C=C1NC4=NC=CC(C5=CC=CN=C5)=N4
Molecular Formula
C29H29N7O2
Molecular Weight
507.59
References & Citations
[1]Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108 (8) :1657-1666.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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