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Melengestrol acetate-d3

CAT: 0804-HY-111614S2Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111614S2Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Melengestrol acetate-d3 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].
UNSPSC
12352211
Target
Isotope-Labeled Compounds; Progesterone Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Metabolic Disease
Purity
99.27
Solubility
10 mM in DMSO
Smiles
CC([C@@]1(OC(C([2H])([2H])[2H])=O)C(C[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=C)=O
Molecular Formula
C25H29D3O4
Molecular Weight
399.54
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]G M Padilla, et al. Melengestrol acetate and megestrol acetate are prostatic tumor inhibiting agents. Biochem Cell Biol. 1990 Oct;68 (10) :1181-8.|[3]G W DUNCAN, et al. BIOLOGIC EFFECTS OF MELENGESTROL ACETATE. Fertil Steril. Jul-Aug 1964;15:416-32.|[4]https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/melengestrol-acetate
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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