ISOX-DUAL

• UNSPSC Description :

  ISOX-DUAL is a dual CBP/BRD4 inhibitor with IC50 values of 0.65 μM and 1.5 μM for CBP and BRD4, respectively[1].

• Target Antigen :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/isox-dual.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=C(C2=CC3=C(C=C2)N(CCN4CCOCC4)C(CCC5=CC=C(C=C5)OCCCN(C)C)=N3)C(C)=NO1

• Molecular Weight :

  531.69

• References & Citations :

  [1]Edmonds AK, et, al. Scale-up and optimization of the synthesis of dual CBP/BRD4 inhibitor ISOX-DUAL. Org Biomol Chem. 2022 May 18;20(19):4021-4029.

• Shipping Conditions :

  Room temperature

• Clinical Information :

  No Development Reported

• CAS Number :

  [1962928-22-8]