(S)-WAY 100135 (dihydrochloride)

(S)-WAY 100135 (dihydrochloride)

• CAS Number: 149007-54-5
• UNSPSC Description: (S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].
• Target Antigen: 5-HT Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/s-way-100135-dihydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=C(N2CCN(CC2)C[C@H](C3=CC=CC=C3)C(NC(C)(C)C)=O)C=CC=C1.Cl.Cl
• Molecular Weight: 468.46
• References & Citations: [1]Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.
• Shipping Conditions: Room temperature
• Storage Conditions: Store at room temperature, keep dry and cool
• Clinical Information: No Development Reported